ParkinsonCanadaV1, Main, Exploration, bibRecord, 000637

Multi-contrast unbiased MRI atlas of a Parkinson's disease population.

Identifieur interne : 000637 ( Main/Exploration ); précédent : 000636; suivant : 000638

Multi-contrast unbiased MRI atlas of a Parkinson's disease population.

Auteurs : Yiming Xiao [Canada] ; Vladimir Fonov ; Silvain Bériault ; Fahd Al Subaie ; M Mallar Chakravarty ; Abbas F. Sadikot ; G Bruce Pike ; D Louis Collins

Source :

International journal of computer assisted radiology and surgery [ 1861-6429 ] ; 2015.

RBID : pubmed:24841147

English descriptors

KwdEn :
- Brain (pathology), Contrast Media, Female, Humans, Imaging, Three-Dimensional, Magnetic Resonance Imaging (methods), Male, Middle Aged, Parkinson Disease (diagnosis), Reproducibility of Results, Retrospective Studies.
MESH :
- chemical : Contrast Media.
- diagnosis : Parkinson Disease.
- methods : Magnetic Resonance Imaging.
- pathology : Brain.
- Female, Humans, Imaging, Three-Dimensional, Male, Middle Aged, Reproducibility of Results, Retrospective Studies.

Abstract

Parkinson's disease (PD) is the second leading neurodegenerative disease after Alzheimer's disease. In PD research and its surgical treatment, such as deep brain stimulation (DBS), anatomical structural identification and references for spatial normalization are essential, and human brain atlases/templates are proven highly instrumental. However, two shortcomings affect current templates used for PD. First, many templates are derived from a single healthy subject that is not sufficiently representative of the PD-population anatomy. This may result in suboptimal surgical plans for DBS surgery and biased analysis for morphological studies. Second, commonly used mono-contrast templates lack sufficient image contrast for some subcortical structures (i.e., subthalamic nucleus) and biochemical information (i.e., iron content), a valuable feature in current PD research.

DOI: 10.1007/s11548-014-1068-y
PubMed: 24841147

Affiliations:

Canada

Le document en format XML

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<front><div type="abstract" xml:lang="en">Parkinson's disease (PD) is the second leading neurodegenerative disease after Alzheimer's disease. In PD research and its surgical treatment, such as deep brain stimulation (DBS), anatomical structural identification and references for spatial normalization are essential, and human brain atlases/templates are proven highly instrumental. However, two shortcomings affect current templates used for PD. First, many templates are derived from a single healthy subject that is not sufficiently representative of the PD-population anatomy. This may result in suboptimal surgical plans for DBS surgery and biased analysis for morphological studies. Second, commonly used mono-contrast templates lack sufficient image contrast for some subcortical structures (i.e., subthalamic nucleus) and biochemical information (i.e., iron content), a valuable feature in current PD research.</div>
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La maladie de Parkinson au Canada (serveur d'exploration)

Multi-contrast unbiased MRI atlas of a Parkinson's disease population.

Multi-contrast unbiased MRI atlas of a Parkinson's disease population.

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	La maladie de Parkinson au Canada (serveur d'exploration)
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